Friday, November 22, 2013

XXI. Le Monde du silence [le dynamite]



XXI. Le Monde du silence [le dynamite]

How much groundwater makes its way into the oceans, with isolates
Abbreviated in our transitory breath—Martha Quest’s awareness of an ecstatic
Lightless bottom, with serially positioned marine anthracimycin—Decoupling
Soil nutrients, animating the oral cavity—Amide in a four-membered β-lactam
Ring after penicillin, then cephalosporin, antibiotics—One bond is unconstituted
By the inherited wisdom of plasmids, by four classes of β-lactamases—Detonations

We contract reliably—Either for serpentine benches of Parc Güell, for detonation
Within barrier reefs—After the blast, parchment worms drain off an isolated
White water, and distribute its milt—This repository of storms is unconstituted
From The Edge of the Sea, the blowfish’s intensification of red tide—Ecstatic  
Capillary water
—Calcareous algae reformed into trencadís, by incised decoupling
Of bodies, a room is swept, a triggerfish relaxes its beak in a jelly’s drift net—β-lactam

Rings strained by ideal apposition; resonance of the amidic bond is abridged—β-lactam
Cores break so that the bacterium manages to reproduce itself—Watered down, it detonates—
Divisional planes of a circular courtyard—N-acetylglucosamine, N-acetylmuramic acid—Decoupled
Gram-positive cross-linkages by lysozyme—Currents read or reproduced in outflowing tears or saliva isolated
By Martha’s landward movement—A square of pink oilcloth to Radlett Street’s unconstituted
Irresistibility, the working memory’s seven-circuit passage—A young shark wriggles its finback ecstatic

Of withering ashore in its case—Behind these rivulets of words was a great chaos of sound, ecstatic
Mostly untranslated in the angel wing holding the luciferin-luciferase system—β-lactam’s
Necromantic sense—A subsiding swell, the enzyme bonding peptidoglycan is unconstituted—
With the alternating four sidechains and byssus of teichoic acids, and yet the detonation
Superimposes itself—Our submerged bodies pause their timed dissociation, a decoupling
Of brittle arms—Seven seas conceived as one carbon dioxide sink; our spines crumbling, but for an isolated

Iphigenia to seed the ocean with carbonates—Cell remnants exposed, susceptible isolates
Of gram-negative bacteria loosen interleaved lipopolysaccharide—Each unique endotoxin arrays our ecstatic
Defenses—Toll-like receptors conserved in kelp, their predating forests of urchins decouple
Immune cells; the cytokines rake out of circulation as septic shock—Pathogenic β-lactamases
Render frontline antibiotics wasted, and infection rushes to the interstices—The unconstituted
Science; no prophecy for which of our velvet linings will snare on a remote antigenicity—Detonations

Shallowing until there is only sand vitrified and inlaid into a hypostyle ceiling—Detonations
Of drug discovery—Inhibiting cell wall biosynthesis is spouted thoughtlessly, the binary isolates’
Frosted effect on trays counterfeits selective pressures of the body—Now unconstituted,
Cephalosporin antibiotics were pooled from a sewer drain—Unearthing a novel bactericide, by ecstatic
Diving we are bombarded by a particular vivid type of atom, and marine anthracimycin foils decoupling—
A complex molecule as Jujol’s polychromy, could collapse at a touch, although the β-lactam

Derivatives as melting glaciers have adherents; faithful to the hallucination of β-lactamase detonations
Of one bond—A reef is unconstituted by dynamite, a rebreathing diver—We live for the ecstatic fall of one tide
For another—In a balloon fish isolated by a hook; spray of water draining out, life reaches its fullest development, and is decoupled.

3 comments:

Σφιγξ said...

I thought about you prior to reading the The Children of Violence tetrology. I should revisit Martha Quest.

Σφιγξ said...

Complicated UTI with pyelonephritis and calculi; after the nephrostomy tube was placed to relieve the acute hydronephrosis, she became tachycardia, hyperthermic (106 rectal)...septic, from a highly perfused colony of ESBL Gram negative bacteria with lipopolysaccharide endotoxins promoting vascular collapse? Invanz/ertapenem, a carbapenem, treats complicated UTIs as a last resort, given its liver toxicity. What did we learn today? Pretreat with abx prior to interventions? With a fever and symptomatic? Yes.

Carbapenems like imipenem were synthesizeds by Merck from Streptomyces cattelya-derived thienamycin (1976).

Σφιγξ said...

*tachycardic

Abx under question from S. cattleya:

http://prod.hopkins-abxguide.org/antibiotics/antibacterial/carbapenem/ertapenem.html?contentInstanceId=254782&siteId=153


https://books.google.com/books?id=PONa-dv63eEC&pg=PA455&dq=Streptomyces+cattleya+Thienamycin+1976&hl=en&sa=X&ved=0ahUKEwie7IWP5b7fAhUB2FkKHYaLDB4Q6AEINTAD#v=onepage&q=Streptomyces%20cattleya%20Thienamycin%201976&f=false

https://microbewiki.kenyon.edu/index.php/Carbapenem-resistant_Enterobacteriaceae_(CRE)